The application of gas separation COFs resin has a wide prospect. COFs have the advantages of programmability, high specific surface area and porosity, and are suitable for gas separation. Its unique structure enables efficient separation selectivity, especially in the separation of oxygen and carbon dioxide. By optimizing the structure and performance, the efficiency and stability of COFs in gas separation are expected to be further improved. With the advancement of synthetic technology, more functional COFs materials may appear in the future, bringing more innovative applications in the field of gas separation.